Singla Lab · Biosciences & Bioengineering
The Singla Lab at IIT Roorkee builds computational frameworks that bridge biology, data science and engineering — cellular architecture from tomography, AI for healthcare diagnostics, and Sanskrit language models.
“Story telling is essentially a data integration process.”
Jitin Singla
What we work on
Cellular architecture
Soft X-ray tomography (SXT) rapidly maps ultrastructure across whole, intact cells. We build the tools that turn those volumes into measurable biology.
AI for healthcare
Jaundice affects 60–80% of newborns worldwide. A phone camera should be enough to triage it.
Low-resource NLP
Sanskrit is morphologically rich and data-poor — exactly the regime where modern NLP is weakest.
Principal Investigator
Assistant Professor · Department of Biosciences and Bioengineering, IIT Roorkee
I am an Assistant Professor in the Department of Biosciences and Bioengineering at IIT Roorkee. My research group develops computational frameworks that bridge biology, data science and engineering — specifically, problems in computational biology and AI-driven bioimage analysis for healthcare diagnostics. More recently we have begun an adventure into Sanskrit-AI tools.
Our current projects span computational characterization of cellular architecture, AI-based jaundice detection, ECG analysis, and AI models for Sanskrit.
Education
Recent work
Identification and characterization of bifunctional pyrophosphate-fructose-6-phosphate 1-phosphotransferase from citrus greening disease-causing α-proteobacterium
Prakash, S. K., Arun, E., Rathore, K., Gubyad, M., Ghosh, D. K., Sharma, A. K.* (corresponding author), & Singla, J.* (corresponding author)
BBA - Proteins and Proteomics, Accepted
Nanobody engineering for next-generation therapeutics
Handa, T., Agarwal, V., Kumar, R., Singla, J., & Tomar, S.
Computational and Experimental Approaches in Protein Engineering and Design, Academic Press, 487–544
YOLO-LAN: Precise Polyp Detection via Optimized Loss, Augmentations and Negatives
Gupta, S., & Singla, J.
IEEE Access
Teaching LLMs to Generate Challenging MILP Instances via Solver Feedback
Singla, J., Pareek, P., Jawanpuria, P., & Singla, P.
Submitted to ICLR 2027, arXiv:2609.37356
Cross-Model Agreement as a Deployment-Time Reliability Signal for Automatic Polyp Segmentation
Gupta, S., & Singla, J.
arXiv preprint, arXiv:2609.10495
Lab notes
2026
Morphotype-resolved 3D morphometry of mitochondrial networks accepted in Structure, and robust mitochondria segmentation with soft X-ray tomography published in the Journal of Structural Biology.
March 2026
Divyanshu Bathla, a doctoral student in the lab, has received the IndiaAI PhD Fellowship for his work building Sanskrit-AI tools. A national initiative under the IndiaAI Mission, it supports full-time doctoral researchers in AI with a monthly stipend of ₹70,000–80,000, an annual research grant of ₹2 lakh, and conference travel support of up to ₹1 lakh.
6 December 2025
Prof. Parikshit Pareek and Jitin Singla engaged with attendees at MMTTC as part of a Faculty Development Programme on “Harnessing AI in Higher Education for an Innovative Future”.
Collaborating with
We look for people who want to build, question and grow — not collect credentials.